Living with allergies or asthma can feel exhausting — especially when symptoms keep coming back no matter what you try. From constant sneezing and sinus pressure to skin rashes or breathing trouble, allergies can quietly affect your daily life, focus, sleep, and confidence. The good news is that specialized allergy clinics can help you find the real cause of your symptoms and guide you toward long-term relief.
Below is a carefully curated list of the 5 best allergy clinics in Fresno and Merced. These clinics are known for focused allergy, asthma, and sinus care. They are listed only from Fresno and Merced, include addresses, and Sierra Allergy is placed at number 1, as requested.
This guide uses simple language and a semantic keyword approach to help readers easily understand their options.
Why choosing the right allergy clinic is important
Allergies are not one-size-fits-all. What triggers symptoms in one person may not affect another at all. A good allergy clinic does more than prescribe medicine — it helps you understand:
- What you are allergic to
- Why symptoms get worse during certain seasons
- How allergies connect with asthma, sinus issues, or skin conditions
- How to prevent flare-ups, not just treat them
The right clinic can improve your quality of life over time, not just give temporary relief.
1) Sierra Allergy Asthma and Sinus Center
Sierra Allergy Asthma and Sinus Center stands out because it offers complete allergy, asthma, and sinus care under one roof. With locations in both Fresno and Merced, it is a convenient and trusted option for patients who want consistent, long-term care close to home.
This clinic focuses on identifying root causes through proper testing and then building personalized treatment plans. Patients commonly visit for seasonal allergies, asthma control, sinus problems, eczema, hives, food allergies, and chronic cough.
Addresses:
- Fresno: 5043 E Cesar Chavez Blvd, Suite 104, Fresno, CA 93727
- Fresno: 7407 N Cedar Ave, Suite 102, Fresno, CA 93720
- Merced: 105 W El Portal Dr, Suite B, Merced, CA 95348
Why it ranks #1:
- Locations in both Fresno and Merced
- Focus on long-term allergy relief, not quick fixes
- Treats children and adults
- Combines allergy, asthma, and sinus care
2) Demere Allergy Asthma & ENT Center (Fresno)
Demere Allergy Asthma & ENT Center is a well-known Fresno clinic specializing in allergy and asthma care. It is often chosen by patients who want a focused immunology-based approach to treating chronic symptoms.
This clinic commonly treats allergic rhinitis (hay fever), asthma, sinus allergies, and immune-related conditions.
Address:
- 540 E Herndon Ave, Suite 101, Fresno, CA 93720
Why people choose it:
- Dedicated allergy and asthma specialty care
- Established presence in North Fresno
- Suitable for ongoing allergy management
3) Sidhu Allergy (Fresno)
Sidhu Allergy is another Fresno-based option for patients looking for specialized allergy and asthma services. The clinic focuses on diagnosing allergic triggers and helping patients manage symptoms through structured treatment plans.
It is a practical choice for people dealing with repeated allergy flare-ups or asthma symptoms that need expert attention.
Address:
- 7151 N Cedar Ave, Suite 103, Fresno, CA 93720
Why it may be right for you:
- Focus on allergy testing and asthma care
- Convenient Fresno location
- Suitable for long-term allergy follow-up
4) Allergy Institute (Fresno)
The Allergy Institute in Fresno is another option patients explore when they need specialty care offered by trained allergists. It is commonly associated with allergy testing and treatment for environmental and seasonal triggers.
Address:
- 7375 N Fresno St, Suite 101, Fresno, CA 93720
Why patients consider it:
- Focused allergy and immunology services
- Accessible Fresno location
- Suitable for chronic allergy sufferers
5) Baz Allergy Asthma And Sinus Center (Merced)
For residents of Merced, Baz Allergy Asthma and Sinus Center is a local option offering care for allergy- and asthma-related conditions. It is a helpful choice for patients who prefer treatment close to home without traveling to Fresno.
Address:
- 360 E Yosemite Ave, Suite 200, Merced, CA 95340
Why it can be helpful:
- Local Merced-based allergy care
- Treats asthma, allergies, and sinus issues
- Convenient for ongoing visits
How to choose the best allergy clinic for you
Before booking an appointment, ask yourself a few simple questions:
- Are your symptoms seasonal or year-round?
- Do you also have asthma, sinus pressure, or skin reactions?
- Do you need regular follow-ups or allergy shots?
- Is location important for repeat visits?
The best clinic is the one that listens to you, explains your condition clearly, and helps you prevent symptoms — not just manage them.
Final thoughts
Finding the right allergy clinic can be life-changing. Whether you live in Fresno or Merced, you have access to experienced clinics that focus on allergy, asthma, and sinus care. If you want comprehensive care with multiple locations, Sierra Allergy Asthma and Sinus Center is a strong place to start.

